Typhoid Fever
Typhoid fever is an acute, life-threatening febrile illness caused by the bacterium Salmonella enterica serotype Typhi.
Location
Risk is greatest for travelers to South Asia and developing countries in Asia, Africa, the Caribbean, and Central and South America. Travelers to South Asia are at highest risk for infections that are nalidixic acid-resistant or multidrug-resistant
Symptoms
high fever as high as 103° to 104° F (39° to 40° C), headache, malaise, loss of apetite, a rash of flat, rose-colored spots, and a slowing of the heart rate. Also many mild and atypical infections occur.
Prevention (vaccine)
VACCINE
Two oral typhoid vaccines are currently available in the United States: Both vaccines protect 50%-80% of recipients. An injection version is still available in other countries
- immunocompromised travelers should not take oral vaccinations
